Your gateway to the Eternal City, Civitavecchia has served as Rome’s seaport since the 13th century. The port has a long and venerable history. The emperor Trajan built a pleasure villa near the modern city, while Bernini and Michelangelo designed the harbor fortifications.

Yet the Eternal City eternally beckons. The ancient capital of the Western World and the center of Christianity for nearly 2,000 years, Rome provides an inexhaustible feast. Visit the ruins of the Forum, view the splendors of the Sistine Chapel, or climb the Spanish Steps, once the heart of Rome’s Bohemian Quarter.

Rome has been a magnet luring the world’s greatest artists, architects, and philosophers since the days of the Caesars.

Italy’s third-largest city, Naples is a bustling metropolis famed for it stately buildings, crowded streets, pizza – and notoriously bad traffic. However, this beautiful city is rich in centuries-old culture and customs. Naples is also your gateway to the Isle of Capri, the fabled Amalfi Coast and the ruins of Pompeii, buried in ash by the cataclysmic eruption of Mt. Vesuvius in 79 A.D.

Naples boasts an ideal location, with both the ruins of Roman cities and the stunning Amalfi Coast in easy reach.

Messina has played a major role in European history since its founding as a Greek colony in the 8th century B.C. During the Roman Empire, the city was a major port and commercial center, during the Middle Ages, Messina was the major port of departure for Crusaders. History has also left its scars: a massive earthquake leveled much of the city in 1908 and the World War II campaign for Sicily devastated Messina. Yet Messina emerged from that devastation with some of its historic treasures intact, including the 12th-century Annunziata dei Catalani Church. Messina is also your gateway to the rugged beauty of southeast Sicily, from the seaside resort of Taormina to Mt. Etna.

Between the fall of Rome and the 1861 unification of Italy, the Arabs, the Normans, the Germans, the Spanish and the French ruled Sicily.

Malta is the largest in a group of seven islands that occupy a strategic position between Europe and Africa. The island’s history is long and turbulent. Everyone from the Normans to the Nazis have vied for control of this small, honey-colored rock. For centuries the island was the possession of the knightly Order of St. John – the Knights Hospitaller. Valletta, Malta’s current capital, was planned by the Order’s Grandmaster Jean de la Valette to secure the island’s eastern coast from Turk incursions. Founded in 1566, Valletta’s bustling streets are lined with superb Baroque buildings and churches.

Malta has a long history: the megalithic stone temples at Gozo may be the oldest freestanding structures on Earth. Malta has two official languages, Maltese (constitutionally the national language) and English. Malta was admitted to the European Union in 2004 and in 2008 became part of the eurozone.

Perched on the west coast of the Peloponnesus, Greece’s largest peninsula, this sleepy fishing village of some 300 souls is your gateway to Olympia, site of the original Olympic Games. Held every four years between 776 B.C. and 393 A.D., when the Emperor Theodosius banned pagan festivals, the Olympic Games celebrated the ideal harmony of mind and body. Every four years, the sacred flame of Altis is rekindled to light the torch for the Modern Games.

Olympia’s temples were destroyed after the games were banned. An earthquake in the 6th century compounded the destruction, and floods buried the site. Excavation of the ruins began in 1875, and Olympia was declared a National Park in 1976.

Kotor lies at the head of Boka Bay. Bordered by towering limestone cliffs, the winding bay is actually Southern Europe’s longest and most dramatic fjord. The port itself is a medieval gem: its narrow, asymmetrical streets are lined with ancient stone houses, old palaces, and churches dating from the 12th century. Kotor is also your gateway to the cultural and scenic wonders of Montenegro, from the old royal capital at Cetinje to the marshes and wildlife of Lake Skadar National Park.

Kotor is renowned for its nightlife: the streets of the old port are lined with pubs, taverns and cafés. The city is also host to a renowned summer carnival.

Kotor is an anchorage port. Passengers transfer to shore via ship’s tender.

Did the catastrophic volcanic eruption that ravaged Santorini circa 1600 B.C. destroy Crete’s ancient Minoan civilization – and give birth to the myth of Atlantis? In 1967, archaeologists on Santorini unearthed the remains of a Bronze Age city that may have been home to as many as 30,000 people. Whether the Lost Continent of Atlantis is rooted in myth or reality, an undisputed fact remains. The eruption created a caldera – and one of the most dramatic land and seascapes in the entire Mediterranean. On Santorini, whitewashed buildings cling to vertiginous cliffs that plunge to a turquoise sea. Part of the Cyclades Archipelago, the three-island group of Santorini, Thirasia and uninhabited Aspronisi present the traveler with unforgettable vistas.

The island has had a number of names throughout history – from Strongyle or “Round” to Thera in honor of an ancient hero. Santorini is more recent and stems from the island church dedicated to St. Irene – Santa Rini to foreign sailors.

From the port of Kusadasi on Turkey’s Anatolian Coast, one travels into the past. Nearby stand the ruins of ancient Ephesus, a major site of archeological excavation. The city was once a Roman provincial capital and trading center. Ephesus is also home to several of Christendom’s holiest sites. St. Paul preached at the Great Theater and the ruins of Ephesus’ Basilica cover the tomb of Christ’s most beloved disciple, St. John the Apostle.

In Kusadasi, whitewashed stone houses rise in tiers behind the market district. The palm-lined esplanade is the center of town life, with thousands of merchants offering wares to rival the Grand Bazaar in Istanbul.

Istanbul rises from the Bosphorus, a vision of minarets and domes sparkling in the light. The capital of vanished empires, Istanbul is a true crossroad, the only city on Earth to span two continents. This meeting place of Europe and Asia, of Christian and Muslim, is one of the great adventures a traveler encounters. Browse the stalls of the world’s largest bazaar, explore ancient mosques and churches, and gaze at the stunning jewels in the Topkapi Palace.

Istanbul has dominated the Straits of Bosphorus for 25 centuries. As Constantinople, capital of the Eastern Roman Empire, it was a metropolis of stunning splendor when the great cities of Europe were mere villages.

The past maintains a vibrant presence in the cradle of Western civilization. Atop the Acropolis, the serene Parthenon sails above the commotion of the modern city. The tragedies of Aeschylus, Sophocles, and Euripides were performed in the Theater of Dionysus at the foot of the Acropolis. On Pnyx Hill, citizens of a fledgling democracy gathered to cast their votes on Athens’ destiny. Then there is the hustle and bustle of the modern city, a metropolis of 4.5 million that spreads out from the foot of Mt. Lycabettus and across the plain. Packed with busy shops and lively tavernas, modern Athens is a colorful counterpoint to classical Greece.

Piraeus is the port city for Athens and has been Athens’ port of entry for over two millennia.